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DOI Number: 10.59152

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Latest Articles

Research Article

Compare Therapeutic Treatment Analysis of Neuro Developmental Versus Non NDT Approach for the Management of 3-8 Years Old Little Disease

Karthikeyan T*
Associated Factors of Underweight Status of Children in Wolkite Health Care Center

A type of little disease in which has prominent therapeutic symptoms of bilateral spasticity, with the lower extremities more severely affected than upper extremity...

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Research Article

Knowledge, Attitude and Practice of Post Exposure Prophylaxis for Hiv Among Healthcare Workers in Two Tertiary Hospitals In Enugu Southeast Nigeria

Enneoka Virginia*, Ogbonna Brian*#, Anetoh Maureen, Ejieh Loveth, Ijeoma Leo-Nnadi, Okpalanma Nneoma, Maduekwe Hilda, Okeke Anthony, Okoye Ifunanya, Osuafor Nkeiruka, Ovwighose Samuel, Nnamani Monica, Ajagu Nnenna and Ofor Amala
Associated Factors of Underweight Status of Children in Wolkite Health Care Center

Background: Human Immunodeficiency Virus (HIV) infection is a global public health challenge with 1.9 million infected people in Nigeria. World Health Organization (WHO), stated that post exposure prophylaxis (PEP) for HIV can prevent seroconversion after exposure.

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Research Article

Synthesis and Characterization of Silver Nanoparticles as Strong Antimicrobial Agents Using Bacteriocin of A Novel Probiotic Strain of Lactobacillus Pentosus S6 (KU92122)

Nivedita Sharma*, Shakshi Sharma, Pooja Sharma and Moksharthi Sharma

The goal of this study was to use bacteriocin from a probiotic strain of Lactobacillus pentosus S6 (KU92122) to synthesize innovative strong silver nanoparticles (AgNPs)...

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Editorial

Narrowing Time to Treatment Initiation in Non-Small Cell Lung Cancer-Cell-Free DNA Profiling at the Time of Biopsy

Jen-Siong Ye and Shu-Ti Lin*

Lung cancer is among the most common malignant diseases and currently the leading cause of cancer-related deaths in the US and worldwide..

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Case Report

A case report of Cogan syndrome based on clinical manifestations with dramatic response to immunosuppressive therapy

Mohamad S*, Akhtarzai A and Zaqoot S

Cogan's syndrome is a rare inflammatory disorder mainly affecting ocular and audio vestibular system. The typical picture are of interstitial keratitis and sudden onset of Meniere-like attacks (nausea, vomiting, tinnitus, vertigo and hearing loss).

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Research Article

No One is Leaving this Time: Appraisal of Awareness and Knowledge of Port Health Officers on International Health Regulation IHR (2005)

Adiama YB*, Solomon Olayinka Adewoye, Opasola Afolabi Olaniyi, Habeeb Modupe Lateefat, Abdullahi Ahmed and Morufu Olalekan Raimi*
Associated Factors of Underweight Status of Children in Wolkite Health Care Center

Background: Historically, ships have played an important role in transmitting infectious diseases around the world. The spread of cholera pandemics in the 19th century was thought to be linked to trade routes and facilitated by merchant shipping...

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Research Article

Residents' Perception on Central Storage of Solid Wastes in Ilorin Metropolis, Kwara State, Nigeria

Yusuf Olanrewaju Raufu, Adewoye Solomon Olayinka and Sawyerr Henry Olawale*
Associated Factors of Underweight Status of Children in Wolkite Health Care Center

Background: Solid waste management in Nigeria has been a major concern to stakeholders due to inefficient collection and unsafe disposal...

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Research article

Colonic Volvulus in Children: A Single Center Experience

Chukwubuike Kevin Emeka, Onah Livinus Nnanyereugo and Anijunsi Livinus Patrick

Background: Colonic volvulus is an uncommon cause of bowel obstruction in children. The aim of this study was to evaluate our experience in the management of children who were confirmed to have colonic volvulus at surgery.

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Editorial

Molecular Histopathology of Benign Uterine Mesenchymal Tumors.

Takuma Hayashi*; Nobuo Yaegashi; Susumu Tonegawa and Ikuo Konishi

Uterine leiomyoma is a benign tumor that develops in the myometrium of the uterus. Estrogen is involved in the development and increase of uterine leiomyoma, and even in patients who had strong symptoms before menopause, uterine leiomyoma significantly shrinks after menopause...

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Research Article

Evaluating the Interactions between Endothelial and Smooth Muscle Cells in the Presence of Drug-Eluting Stents and Platelets: Is Interleukin6 a New Possible Therapeutic Target for In-Stent Restenosis?

Clarissa Campo Dall'Orto*, Daniel da Conceicao Rabelo, Rosely Cabette Barbosa Alves, and Durvanei Augusto Maria

The success of percutaneous coronary intervention (PCI) procedures is limited by in-stent restenosis (ISR). The use of drug-eluting stents (DES) decreased the incidence of ISR; however, ISR continues to affect a percentage of patients with ischemic cardiac events...

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Research Article

The Impact of Covid-19 on Use of Certified Seeds and Grain Production of Cowpea and Sorghum Varieties in Northern Nigeria

Isaiah Gabriel*, Frank Olajuwon, Blessing Michael

This study was conducted to evaluate the Impact of Covid-19 on certified seeds and grain production of cowpea and sorghum varieties in Northern Nigeria.

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Research Article

Experimental Evidence of Antidiabetic Herbs

K Nishteswar*

Plant drugs play an important role in the development of single chemical entities for therapeutic purposes. The economically developed countries are evincing keen interest in the so called alternative systems, in which remedies based on herbal drugs are playing an important role.

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Research Article

Assessment of the Efficacy and Safety of the Instantaneous Wave-Free Ratio in a Real-World Setting

Clarissa Campo Dall'Orto*, Rubens Pierry Ferreira Lopes, Gilvan Vilella Pinto Filho and Marcos Raphael da Silva

Background:The limitations of visual angiographic assessment in coronary artery disease are well known. When intermediate lesions are submitted for functional assessment, there is a reclassification in the initial therapeutic decision in up to 33% of patients...

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Review Article

Where Darwin Neglected to Explain the Human-Brain Encephalization: 2). The Biochemical Model Supporting the "Savanah Dry-Land Hypothesis" (SDLH)

Vincent van Ginneken*

In an earlier review, we suggested the African savannah with its enormous herds of the ancestors of the African buffalo whas the 'driving force' in human encephalization delivering the substances essential to early hominids for their tremendous brain expansion from Homo erectus (average brain volume about 950 cm3 for the African lineage) towards modern Homo sapiens (≈ 1500 cm3 brain)...

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Short Communication

Enabling Circulating Cell-free mRNA Profiling to Empower Cancer Early Detection

Chen-Hsiung Yeh*

DNA methylation occurs early in tumorigenesis and is highly pervasive across cancer types, making it suitable for early detection and intervention of cancer. Gene expression at the transcription level is reflected by epigenetic regulation of chromosome especially DNA methylation, therefore providing a distinct approach to achieve the same goal.

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Case Presentation

Serious Infection of Chest Wall during Radiotherapy in Breast Cancer Patient with Large Seroma: A Case Report and Review of the Literature

Guanqiao Li, Jia Yao, Baizhen Cai, Qiang Fu, Fei Kong, and Shiping Yang*

Background: A seroma is the most common complication after modified radical mastectomy for breast cancer. We could not find any publications about chest wall infections in patients with large seromas during radiotherapy in Pubmed.

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Research Article

Periodontal Disease and Hypertension: A Mechanistic Link between Local and Systemic Inflammation

Muna S. Elburki*

Objective: To explore the link between hypertension and periodontitis and also to inspect the mechanistic link between local and systemic inflammation.

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Case Report

COVID-19 in Children: A Case Report of Multisystem Inflammatory Syndrome (MIS-C) in Tripoli-Libya

Feras Al Lami*, Abdulfattah Bengheshir and Awatif Abushhaiwia

As COVID-19 continues to spread in countries all over the world included Libya, the impact of the disease among children, initially considered less important [1], will increasingly be more relevant. The role of children in viral transmission and its impact in epidemic expansion, as well as the extent of the diversity of clinical presentation, are still unclear...

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Research Article

Comparative Evaluation of Dentin Surface after Preparation by Diamond Bur and Oscillating Tip, with and without Etching

Yusuf-Solieman O*1, Dessouter A2, Ramonda M3, Tassery H4, F. Cuisinier5, Durant JC6 and Fages M7

Objective: Oscillating ultrasonic instruments were basically used to finish marginal preparation, while they produce more rough surfaces, unlike the regular surfaces produced by the rotating diamond instruments. This study aims to investigate the change of dentin roughness after etching using two different preparation tools: diamond bur and diamond ultrasonic tip.

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Case report

Endoscopic Trans-Spheroidal Approach for Embolization of Carotid- Cavernous Fistula without a Hybrid Room, With Relatively Aseptic Procedure.

Chi-Kao Tang, Chee-Tat Lam and Yong-Hui Liu*.

Endovascular embolization is the treatment of choice for Carotid-Cavernous Fistulas (CCFs), but rarely catheterization of the cavernous sinus via venous or arterial pathway is not possible. The authors present one of such cases in which a straightforward route to the CCF...

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Research Article

The Effects of Laser Radiation on Exposed Dentine Surfaces in the Treatment of Dentine Sensitivity. An In Vitro Study

McCarthy D1, Pearson GJ2 , Palmer G2, Gillam DG1,3

Aim: This in vitro pilot study was undertaken to investigate the effects of Neodymium: Yttrium Aluminium Garnet (Nd:YAG), Erbium: Yttrium Aluminium Garnet (Er:YAG) and Helium Neon (HeNe) laser radiation on dentine surfaces in extracted human teeth.

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Short Communication

Differences in Nutritional Risk in Hospitalized Patients versus Primary Care Patients.

De la Torre FJM1*, Pena NB2, Reyes MM1 and Garcia RM1

Introduction: Nutritional status is a determining factor in the progress of diseases. There are different methods for its evaluation, but they generally require many resources. However, the laboratory nutritional risk assessment CONUT, or Control Nutritional (Nutritional Control), is a widely validated, effective alternative.

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Research Article

Loop-Mediated Isothermal Amplification and its Application in Rapid Detection of Microorganisms

Han M, Wu X and Yu D*

Loop-Mediated Isothermal Amplification (LAMP) is a new nucleic acid amplification technique developed by Japanese scientist Notomi [1] in 2000, which is concerned by, scholars all over the world and relevant government departments.

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Research Article

Relationships between Assessment of Diabetes Therapy, Self-Care Behaviors, and Glycemic Control in Outpatients with Type 2 Diabetes Treated with Glucose-Lowering Agents

Katahira M*1, 2, Ogata H2, Asano Y3 and Ito Y3

Objective: The purpose of this study is to investigate the assessment of therapy of Type 2 diabetes (T2D) patients, as well as their self-care behaviors, and clarify how these are related to glycemic control...

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Short Communication

Differential Diagnosis of Asthma: Bronchial Candidiasis.

Benali A*, El Ouazzani H, Rhorfi IR, Souhi H and Abid A.

Bronchial candidiasis are rare respiratory infections whose diagnosis is difficult and often life-threatening, the occurrence of its infections in immunocompetent is rare and it can pose a problem of differential diagnosis with other pathologies such as asthma and bronchial neoplasia...

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Case Report

Risk Factors for Malignant Melanoma in Romania

Monica Deac L*

In all ages of population in the recent decades, Malignant melanoma is the most dangerous type of skin cancer in the whole world. Its incidence has increased worldwide and that for and earlier diagnosis programs, who reduce the morbidity and mortality of the malignant disease...

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Research Article

Mediastinal Haemorrhage Secondary to Spontaneous Perforation of An Aneurysm of A Saphenous Vein Graft to Right Coronary Artery

Hein YP*, Ekladious A, Wynn S

Mediastinal haemorrhage caused by rupture of a saphenous vein coronary artery bypass graft (CABG) is a potentially life-threatening complication following the grafting procedure...

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Research Article

Inflammation of Organs in Autistic Children

Shui Yin Lo*

Following the previous paper "Diagnosis, prevention, and treatment of Autism via Meridian theory" 2012, we continue our work on three aspects of inflammation of organs in autistic children...

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Short Communication

Clinical Characteristics and Management of Cancer Patients with COVID-19

Jingmao Y, Xiaofei L, Liping C, Zhenyu F, Jun L, Rong T and Jilin C*

The epidemic of new coronavirus pneumonia that broke out in Wuhan in December 2019 is beyond doubt a disaster especially for cancer patients. There are limited data on the clinical characteristics of cancer patients with SARS-CoV-2 infection, and treatments based on this aspect are rarely mentioned...

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Case Report

Immunotherapy in Endocrine Responsive Metastatic Breast Cancer

Tabane K MD1* and Vorobiof D, MD2

Immunotherapy has shown great benefit in multiple tumour types like melanoma and lung cancer. Although breast cancer was previously not considered an immunogenic disease...

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Case Report

Nerves Paralysises Associated to Nasal Obstruction : What Is Your Diagnosis ??

Ilham Rkain1,2*, Safaa Touihmi1 and Hicham mimouni3

A 60 year old man presented with complaints of nasal obstruction (left side), smell disorder , headache and neuralgia on the left side of his face for 2 years, ptosis and diplopia followed by reduction vision of the left side...

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Research Article

Relationship between Patient Understanding and Compliance with Rheumatic Heart Disease Prevention Programs in American Samoa

Jennifer H. Huang MD1*, Callia Elkhal MD2, Ipuniuesea Eliapo-Unutoa3, Laurie R. Armsby MD4 and Erin J. Madriago MD5

Objective: While mostly eradicated in developed nations, rheumatic heart disease (RHD), is still the leading cause of preventable cardiovascular disease in children...

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Research Article

Nutrition Labelling: We Need a New European Algorithm

Roberto Volpe1* and Stefania Maggi2

People often choose and buy foods depending on factors such as personal preferences, price, their age, economic and socio-cultural position...

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Case Report

Chronic Pancreatitis-Induced Colonic Obstruction Mimicking a Stenosing Neoplasm at the Proximal Descending Colon: Treatment by Diverting Colostomy and Serial Pancreatic Duct Stenting

Ying Lun Wei, M.D and Kevin A. Wang*

Large bowel obstruction mimicking colon cancer is a rare complication of acute or chronic pancreatitis. We present a case of a 42-year-old male patient with chronic alcoholic pancreatitis presenting with abdominal distension for two months...

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Review Article

Candida-Associated Gastric Ulcerrevisited

Kenji Sasaki*

Candida-associated gastric ulcer occurs not only in debilitated but healthy individuals. Though had been reported to demonstrate nothing but nonspecific endoscopic features, it occasionally exhibits a typical finding I designated a candidarium...

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Review Article

Enhancing Reproductive Performance in Dairy Buffalo

Luigi Zicarelli*

The aim of the review is to report on some of the factors affecting fertility in buffalo and the techniques that allow an improvement of the reproductive performance...

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Mini Review

Enhancing Medical Treatment Support in Geriatrics and Further Reducing the Mortality of Elderly Novel Coronavirus Disease Patients

Li-Hua Li*

The coronavirus disease 2019 (COVID-19) has evolved into a serious global emergency and led to a large number of deaths.Elderly COVID-19 patients have a higher mortality rate than those with younger age...

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Research Article

Pulmonary Embolism Associated With Thrombi of the Right Heart: What Appropriate Care? Clinical Case and Literature Review

Taryètba A. Arthur Seghda1*, Miguel A.M Lopez1, Théodore Boro2, Issa Sawadogo1, Aminata Niakara3, Saidou Dimzouré1, Georges R.C Millogo4, Nobila V Yaméogo4, Elodie Sib5, André Samadoulougou1 and Patrice Zabsonré4

Pulmonary embolism associated with right heart thrombi mainly in the atrium, raise therapeutic dilemmas. Their relative rarity does not allow the development of a consensus recommendation for standardized treatment...

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Case Report

Novel ATP2A2 Gene Mutation c.118G>A Causing Keratinocyte and Cardiomyocyte Disconnection in Darier Disease

Andrea Frustaci, MD1,2*, Alessandro de Luca, PhD3, Romina Verardo, BSB2, Claudia Grande, BSB2, Valentina Guida, PhD3, Maria Alfarano, MD1, Francesco Petrizzelli, PhD4, Tommaso Biagini, PhD4, Camilla Calvieri, MD1, Matteo Antonio Russo, MD2,5 and Cristina Chimenti, MD, PhD1,2

Objective: Darier disease (DD) is an autosomal dominant disorder due to mutation of ATP2A2 gene causing an isolated skin manifestation based on keratinocyte disconnection and apoptosis...

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Case Report

Kleine Levine syndrome (Sleeping beauty): A case report from Saudi Arabia

Wadha Alotaibi, MD1 and Gawahir Mukhtar, MD2*

Background: Kleine – Levin syndrome (KLS), also called “Sleeping beauty syndrome” is a rare sleep disorder characterized by recurrent episodes of hypersomnia, hyperphagia, cognitive disturbances, and hypersexuality.

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Review Article

Viruses: Genetically Encoded Alarm Messages for Communication between Individuals

Alejandro Sousa*

According to the present alert information theory, viruses are not microorganisms external to our body, but their genetic material is already contained in the DNA/RNA of our cells, in what we know as endogenous retroviruses (ERVs)...

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