Download PDF

ES Journal of Clinical Medicine

ISSN: 2768-010X

Decrease in the Oxygen Extraction Ratio in Surgical Patients after Blood Transfusion

  • Research Article

  • Víctor Alfonso Elizondo Leal1, Airam Regalado Ceballos2, Luis Javier Marfil Rivera3, Rodolfo Morales Ávalos4*, Dionicio Palacios Ríos1, and Ana María Espinosa Galindo1
  • 1Department of Anesthesiology, School of Medicine and University Hospital “Dr. José Eleuterio González”, Universidad Autonoma de Nuevo León (U.A.N.L.) Universidad Autónoma de Nuevo León, México
  • 2School of Medicine and University Hospital “Dr. JoséEleuterio González”, Universidad Autonoma de Nuevo León (U.A.N.L.) Universidad Autónoma de Nuevo León, México
  • 3Department of Hematology, School of Medicine and University Hospital “Dr. José Eleuterio González”, Universidad Autonoma de Nuevo León (U.A.N.L.) Universidad Autónoma de Nuevo León, México
  • 4Department of Orthopedic Surgery and Traumatology, School of Medicine and University Hospital “Dr. José Eleuterio González”, Universidad Autonoma de Nuevo León (U.A.N.L.) Universidad Autónoma de Nuevo León, México
  • *Corresponding author: Rodolfo MoralesAvalos, Department of Orthopedic Surgery and Traumatology, School of Medicine and University Hospital “Dr. José Eleuterio González”, Universidad Autonoma de Nuevo León (U.A.N.L.) 4th Floor of the Central Building of the University Hospital. Av. Francisco I. Madero and Av. Dr. Eduardo Aguirre Pequeño, s/n, Col. Mitras Centro, C.P. 64460. Monterrey, Nuevo León, México
  • Received: Apr 23, 2020; Accepted: May 29, 2020; Published: June 08, 2020

Abstract

Introduction: To establish if there is a relationship between the decrease in the oxygen extraction ratio (O2ER) and the administration of erythrocyte concentrate (EC) using central venous saturation for the calculation of O2ER.

Method: Samples were obtained for blood gas analysis before starting the transfusion and 15 minutes after EC administration. Changes related to blood transfusion in patients with O2ER < 45% and > 45% were analyzed. The statistical test of paired T was used to compare both groups.

Results: Thirty patients were included, of which 5 were eliminated due to massive bleeding and 25 patients were followed, 14 men (56%) and 11 women (44%) Prior to transfusion, 16 patients (64%) showed a O2ER < 45% with a mean of 26.8 + 8.06% without significant change in post-transfusion O2ER and 9 patients (36%) reported a O2ER > 45% with a mean of 50.07 + 5.12%. having a significant decrease of -10.26 (-23.93 to -5.77) in O2ER; p <0.001.

Conclusions: After the transfusion of CE, there was a significant decrease in that of O2ER in the patients that presented a value > 45% before transfusion.

Keywords

Blood transfusion; Central venous catheter; Hemorrhage; Hemoglobin; Oxygen extraction ratio

Citation: Leal VAE, Ceballos AR, Rivera LJM, Ávalos RM, Ríos DP and Galindo AME. Decrease in the Oxygen Extraction Ratio in Surgical Patients after Blood Transfusion. ES J Clin Med. 2020; 1(3): 1017.