ES Journal of Case Reports

ISSN: 2767-6560

Ichthyosis Follicularis with Alopecia and Photophobia Syndrome (IFAP): A Case Report and Review of the Literature

Case Report
Elharrouni Alaoui Aicha*, Baybay Hanane, Douhi Zakia, Elloudi Sara, and Mernissi FZ
Department of Dermatology, CHU Hassan II, Morocco
*Corresponding author: El harrouni Alaoui .A, Department of dermatology ,CHU Hassan II, FES, Morocco
Received: May 23, 2020;Accepted: June 12, 2020; Published: June 15, 2020;

Abstract

IFAP syndromeis a rare autosomal recessive X-linked disease characterized by the triad of alopecia universalis, severe photophobia, and follicular ichthyosis. It is caused by loss of function of the gene MBTPS2. Its severity varies and there are only a few reports in the literature. We present a patient with characteristic clinical features.

Keywords

Ichthyosis Follicularis; Atrichia; Photophobia; X-linked; MBTPS2 gene; IFAP syndrome